Cytochrome c protein and assay

Details Cytochrome c protein and assay Cytochrome c protein and assay

2004-12-17

2011-12-13

Monshipouri, Maryam (Department: 1656)

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

C435S252300, C435S320100, C530S350000, C536S023100

Reexamination Certificate

active

08076148

ABSTRACT:
The present invention relates to a cytochrome c-reporter fusion protein construct comprising a modified cytochrome c protein which targets the mitochondria and has a reduced ability to induce apoptosis in a living cell. The invention also relates to nucleic acid constructs encoding such protein fusions and cells stably transfected with such constructs. The stably transfected cells of the invention can be used in assays to detect apoptosis.

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