Cytochrome c oxidase enzyme complex

Details Cytochrome c oxidase enzyme complex Cytochrome c oxidase enzyme complex

2005-01-26

2010-11-30

Ramirez, Delia M (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

C435S189000, C435S320100, C435S252300, C435S069100, C530S350000, C536S023200

Reexamination Certificate

active

07842483

ABSTRACT:
The present invention is directed to a novel cytochrome c oxidase complex, genetic materials useful for the preparation of the said complex, such as recombinant polypeptides involved in cytochrome c oxidase complex, recombinant DNA fragments, expression vectors, recombinant organisms and the like. Those novel cytochrome c oxidase complex and genetic materials may be originated from a microorganism having the identifying characteristics ofGluconobacter oxydansDSM 4025. The present invention also provides a method for the preparation of the said novel recombinant cytochrome c oxidase complex and a process for the production of 2-keto-L-gulonic acid (2KGA).

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Ludwig, et al., “A Kinetic Study of the Oxidation by Molecular Oxygen of the Cytochrome Chain of Intact Yeast Cells,Acetobacter suboxydansCells, and of Particulate Suspensions of Heart Muscle,” Enzyme, vol. 29, pp. 73-85 (1983).
Cao, et al., “Cytochrome aa3 ofRhodobacter sphaeroidesas a Model for Mitochondrial Cytochrome c Oxidase,” The Journal of Biological Chemistry, vol. 267(34), pp. 24273-24278 (1992).
Ostermeier, et al., “Structure at 2.7 Å resolution of theParacoccus denitrificanstwo-subunit cytochrome c oxidase complexed with an antibody Fv fragment,” Proc. Natl. Acad. Sci., vol. 94, pp. 10547-10553 (1997).
Raitio, M., et al., Database Swissprot Online Abstract No. XP-002206939, (Aug. 1, 1988).
Raitio, M., et al., Database Swissprot Online Abstract No. XP-002206940, (Nov. 1, 1995).
Raitio, M., et al., Database Swissprot Online Abstract No. XP-002206941, (Aug. 1, 1988).
Raitio, M., et al., Database Swissprot Online Abstract No. XP-002206942, (Aug. 13, 1987).
Raitio, M., et al., Database Swissprot Online Abstract No. XP-002206943, (Feb. 1, 1994).
Raitio, M., et al., Database Swissprot Online Abstract No. XP-002206944, (Feb. 1, 1994).
Ludwig, et al., “A Kinetic Study of the Oxidation by Molecular Oxygen of the Cytochrome Chain of Intact Yeast Cells,Acetobacter suboxydansCells, and of Particulate Suspensions of Heart Muscle”Enzyme, vol. 29, pp. 73-85 (1983).
Cao, et al., “Cytochrome aa3ofRhodobacter sphaeroidesas a Model for Mitochondrial Cytochrome c Oxidase,”The Journal of Biological Chemistry, vol. 267(34), pp. 24273-24278 (1992).
Ostermeier, et al., “Structure at 2.7 Å resolution of theParacoccus denitrificanstwo-submit cytochrome c oxidase complexed with an antibody Fvfragment,”Proc. Natl. Acad. Sci., vol. 94, pp. 10547-10553 (1997).

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