Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Reexamination Certificate
2006-04-18
2006-04-18
Priebe, Scott D. (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
C800S021000, C800S014000, C435S325000, C435S354000
Reexamination Certificate
active
07030291
ABSTRACT:
The present invention relates to compositions and methods relating to the characterization and function of CYT28. Specifically, the present invention provides transgenic animals comprising disruptions in a CYT28 gene and methods of treating diseases conditions, such as pain. The present invention further relates to agents that modulate CYT28 and methods of screening for agents that modulate CYT28 for the treatment of diseases and conditions such as pain.
REFERENCES:
Gass, 2001, Physiology and Behavior, vol. 73, pp. 8111-8825.
Crawley, 1997, Hormones and Behavior, vol. 31, pp. 197-211.
Belzung, 2001, Behavioral Brain Research, vol. 125, pp. 141-149.
Leonard, 1995, Immunological Reviews, vol. 148, pp. 98-113.
Griffiths, 1998, Microscopy Research and Technique, vol. 41, pp. 344-358.
Mogil, 1999, Pain, vol. 80, pp. 67-82.
Genbank Accession #AF166382, ROD Oct. 2, 1999.
Mansour, S. Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in tha tail and inner ear. Development, vol. 117, pp. 13-28.
Bartolomei F., Late-onset epilepsy associated with regional brain cortical dysplasia, European Neurology, 42:11-16, 1999.
A. Terskikh et al., “From Hematopoiesis to Neuropoiesis: Evidence of Overlapping Genetic Programs” PNAS, vol. 98, No. 14, Jul. 3. 2001, pp. 7934-7939.
M. Capecchi, “Targeted Gene Replacement” Scientific American, vol. 270, No. 3, Mar. 1994, pp. 34-41.
Bertoglio Valarie
Burke John E.
Deltagen Inc.
Greenberg & Traurig, LLP
Priebe Scott D.
LandOfFree
CYT28 serpentine receptor disruptions, compositions and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with CYT28 serpentine receptor disruptions, compositions and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CYT28 serpentine receptor disruptions, compositions and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3526961