Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1997-04-18
1998-05-19
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
435 6, 4352523, 43525411, 435325, 4353201, 536 232, 536 243, C12N 900, C12N 1500, C12N 120, C07H 2104
Patent
active
057534802
ABSTRACT:
The invention provides cysS polypeptides and DNA (RNA) encoding cysS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing cysS polypeptides to screen for antibacterial compounds.
REFERENCES:
patent: 5429921 (1995-07-01), Harpold et al.
Seror et al. (1994) A Mutant Cysteinyl-tRNA Synthetase Affecting Timing of Chromosomal Replication Initiation in B. subtilis and Conferring Resistance to a Protein Kinase C Inhibitor, EMBO J. 13(10): 2472-2480.
R. Calendar et al., "Purification and Physical Characterization of Tyrosyl Ribonucleic Acid Synthetases from Escerichia coli and Bacillus subtilis", Biochemistry, 5(5) pp. 1681-1690 (1966).
J. Hughes et al., "How Does Pseudomonas Fluorescens, the Producing Organism of the Antibiotic Pseudomonic Acid A, Avoid Suicide?", FEBS Letters, 122(2) pp. 322-324 (1980).
Hou et al., "Sequence determination and modeling of structural motifs for the smallest monomeric aminacyl-tRNA synthetase," Proc. Natl. Acad. Sci., 88 pp. 976-980 (1991).
Fleischmann et al., "Whole-genome random sequencing andassemblyof Haemophilus influenzae Rd., " Science, 269 pp. 496-512 (1995).
Gagnon et al., "Clustering and Co-transcription of the Bacillus Subtilis Genes Encoding the Aminoacyl-tRNA Synthetases Specific for Glutamate and for Cysteine and the First Enzyme for Cysteine Biosynthesis," Journal of Biological Chemistry, 269(10) 7473-7482 (1994).
Sevier et al., "Monoclonal Antibodies in Clinical Immunology," Clinical Chemistry, 27(11) pp. 1797-1806 (1981).
Wolff et al. "Direct Gene Transfer into Mouse Muscle in Vivo," Science, 247 pp. 1465-1468 (1990).
Gimmi Edward R.
Hobbs Lisa J.
King William T.
Lentz Edward T.
SmithKline Beecham Corporation
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