Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2008-08-11
2010-11-09
Wilson, James O (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C544S357000
Reexamination Certificate
active
07829709
ABSTRACT:
The present invention provides cysteine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction.
REFERENCES:
patent: 5589473 (1996-12-01), Geiwiz et al.
patent: 2005/0032708 (2005-02-01), Bush et al.
patent: 2006/0270647 (2006-11-01), Coric et al.
patent: 4228455 (1994-09-01), None
patent: 0463514 (1992-01-01), None
patent: 0499882 (1992-08-01), None
patent: 0999204 (2000-05-01), None
patent: 1004302 (2000-05-01), None
patent: 1120407 (2001-08-01), None
patent: 1195259 (2002-04-01), None
patent: 1364943 (2003-11-01), None
patent: 1374831 (2004-01-01), None
patent: 2159183 (1973-06-01), None
patent: 91/18594 (1991-12-01), None
patent: 97/46229 (1997-12-01), None
patent: 01/37788 (2001-05-01), None
patent: 0211676 (2002-02-01), None
patent: 2004/030522 (2002-04-01), None
patent: 03/045359 (2003-06-01), None
patent: 2004/108692 (2004-12-01), None
patent: 2008008380 (2008-01-01), None
Angehrn, P. et al., “New Antibacterial Agents Derived from the DNA Gyrase Inhibitor Cyclothialidine,” Journal of Medicinal Chemistry, American Chemical Society, Washington, US, vol. 47, No. 6, Jan. 1, 2004, pp. 1487-1513.
Braga, A. L. et al., “‘One-Pot’ Synthesis of Chiral N-Protected alpha-Amino Acid-Derived 1,2,4-Oxadiazoles,” Synthesis, May 26, 2004, pp. 1589-1594.
Grzonka, Z. et al., “Chiroptical Properties of Tetrazole Analogs of Amino Acids,” Polish Journal of Chemistry, vol. 52, 1978, pp. 1411-1413.
Brook, et al. “Tetrazole analogues of amino acids and peptides: II. Paper and thin-layer chromatography of tetrazole analogues of amino acids,” Journal of Chomatography, vol. 15, No. 2, 1970, pp. 310-313.
Shumpei Sakaibara, Hisaya Tani: “Synthesis of Polycysteine,” Bull. Chem. Soc., Japan, vol. 29, 1956, pp. 85-88.
Erwin Brand, Marta Sandberg: “The lability of the sulfur in cystine derivatives and its possible bearing on the constitution of insulin,” J. Biol. Chem., vol. 70, 1926, pp. 381-395.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 5753808 & Marc J. O. Anteunis, Chr. Becu, A. Kolodziejcz;yk, Bogdan Liberek: Bull. Soc. Chim. Belges, vol. 90, No. 8, 1981, pp. 785-802.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 5753809 & A. Kolodziejczyk, Bogdan Liberek: Bull. Soc. Chim. Beiges, vol. 90, No. 8, 1981, pp. 785-802.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 844285 & Blaha et al.: Collection of Czechoslovak Chemical Communications, vol. 31, 1966, pp. 4296-4298.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 3978029 & Blaha et al.: Collection of Czechoslovak Chemical Communications, vol. 31, 1966, pp. 4296-4298.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 3986193 & Blaha et al.: Collection of Czechoslovak Chemical Communications, vol. 31, 1966, pp. 4296-4298.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 72669 & Jesse P. Greenstein: “Studies of multivalent amino acids and peptides” J. Biol. Chem., vol. 118, No. 2, 1937, pp. 321-329.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 800081 & A. P. Hope, B. Halpern: Australian Journal of Chemistry, vol. 29, 1976, pp. 1591-1603.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 665766 & Wenck, Schneider: Experientia, vol. 27, 1971, pp. 20-22.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 60079 & Abderhalden, Rossner: Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie, vol. 163, 1927, p. 183.
G. Zanotti, F. Pinnen, G. Lucente: Tetrahedron Letters, vol. 26, No. 44, 1984, pp. 5481-5484.
Karl-Hans Ongania: “Selektive Eliminations-Additionsreaktionen” Arch. Pharm., vol. 312, 1979, pp. 963-968.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 50666 & Hooper et al.: J. Chem Soc., vol. 1956, 1956, pp. 3148-3151.
Hans Heymann, T. Ginsberg, Z. R. Gulick, E. A. Konopka, R. L. Mayer: “The preparation and some biological properties of the asparagine analog L-2-amino-2-carbocyethanesul fonamide” J. Am. Chem. Soc. vol. 81, 1959, pp. 5125-5128.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 2635366 & Michael Ruf et al.: Chemische Berichte, vol. 129, No. 10, 1996, pp. 1251-1258.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 6702116 & L. Servas, I. Photaki: J. Am. Chem. Soc., vol. 84, 1962, pp. 3887-3897.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 2635070 & Fry: J. Org. Chem., vol. 15, 1950, pp. 438-441.
Database Crossfire Beilstein Bellstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 3187303 & Foeldi: Acto Chimica Academiae Scientarum Hungaricae, vol. 5, 1955, pp. 187-194.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 2611160 & L. Servas, I. Photaki: J. Am. Chem. Soc. , vol. 84, 1962, pp. 3887-3897.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 1730085 & Pirie: Biochemical Journal, vol. 25, 1931, p. 619.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 10718042 & Eiji Kawanishi, Kyoichi Higuchi, Akihiko Ishida: Heterocycles, vol. 52, No. 1, 2000, pp. 425-443.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 10724708 & Eiji Kawanishi, Kyoichi Higuchi, Akihiko Ishida: Heterocycles, vol. 52, No. 1, 2000, pp. 425-443.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 5323681 & A. I. Meyers, Richard A. Amos: J. Am. Chem. Soc., vol. 102, No. 2, 1980, pp. 870-872.
Database Crossfire Beilstein Beilstein Institute Zur Foerderung Der Wissenschaften, Franfurt Am Main, DE; Database accession No. 2200873 & T. Inui: Bull. Soc. Chem. Japan, vol. 44, No. 9, 1971, pp. 2515-2520.
Baker et al. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nat Neurosci 2003; 6: 743-749.
Baker et al. Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclindine. Neuropsychopharmacology 2008; 33: 1760-1772.
Berk M. Oxidative stress in bipolar disorder: a double blind randomized placebo controlled trial of N-actyl cysteine as glutathione precursor. Bipolar Disorders 2007; 9(suppl 1): 21.
Larowe et al. Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals. Am J Addict 2006; 15: 105-110.
Madayag et al. Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine. J Neurosci 2007; 27: 13968-13976.
Mardikian et al. An open-label trial of N-acetylcysteine for the treatment of cocaine depedence: a pilot study. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31: 389-394. .
Moran et
Baker David A.
Cook James M.
Johnson, II Edward Merle
Yin Wenyuan
Marquette University
Quarles & Brady LLP
University of Wisconsin - Milwaukee
Willis Douglas M
Wilson James O
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