Cysteine delivery system

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514369, 514562, A61K 31425, A61K 3123

Patent

active

046650822

ABSTRACT:
L-2-oxothiazolidine-4-carboxylate, a sulfur analog of 5-oxoproline, is cleaved by the enzyme 5-oxo-L-prolinase to form cysteine, thus providing the basis for a cysteine delivery system by the addition of L-2-oxothiazolidine-4-carboxylate to base amino acid solutions or by injecting it directly into in vivo cells.

REFERENCES:
patent: 3974031 (1976-08-01), Yamada et al.
patent: 4006057 (1977-02-01), Sano et al.
Kaneko et al., Bull. Chem. Soc., 37: 242-244, 1964.
PDR, 34th ed, 1980, pp. 1238-1241 and 1730-1732.

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