Organic compounds -- part of the class 532-570 series – Organic compounds – Plural nitrogens bonded directly to the pteridine ring system
Patent
1983-09-06
1984-12-25
Coughlan, Jr., Paul M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Plural nitrogens bonded directly to the pteridine ring system
C07D47508
Patent
active
044905297
ABSTRACT:
Cysteic acid and homocysteic acid analogues of methotrexate and aminopterin having antitumor activity and low toxicity are soluble in water at a physiological pH ranging from 7.2-7.5.
REFERENCES:
patent: 2742468 (1956-04-01), Brockman et al.
Seeger et al., J. Am. Chem. Soc., vol. 71, pp. 1753-1758 (1949).
Coughlan, Jr. Paul M.
Dana-Farber Cancer Institute Inc.
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