Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1985-07-15
1988-11-22
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 424424, 424425, 424426, 935 59, 935 60, 935 64, 514964, 530399, 530412, 530417, A61S 300
Patent
active
047865016
ABSTRACT:
This invention relates to a method for purifying and concentrating biologically active growth hormone to produce growth hormone in a form suitable for incorporation into a controlled release device (or system). A buffered solution of purified recombinant growth hormone is dialyzed against a buffered solution until the salt level is reduced to less than 5% and then lyophilized.
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De Geeter et al, CA vol. 99, 1983, #157232u.
Blackshear, "Implantable Drug Delivery Systems" Scientific American 1979 pp. 66-73.
Janski Alvin M.
Yang Ren-Der
Draper Garnette D.
Farquer Thomas L.
Guffey Wendell R.
International Minerals & Chemical Corp.
Schain Howard E.
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