Cylic imidazole compounds having relatively low hydrogen content

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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5483137, 526258, 526262, 526263, C07D40302, C07D40312, C08F12606, C08F12608, C08F22606

Patent

active

060968990

ABSTRACT:
In one embodiment, the invention provides a polymer comprising imidazole ring units having nitrogen at the 1 and 3 positions of the ring; a carbon at each of the 2, 4 and 5 positions of the ring; and radical substituents G1 and G2 carried at the 4 and 5 positions. G1 and G2 are each independently selected from cyano, substituents derived from cyano, and substituents which replace cyano. The polymers formed by at least two of the cyclic imidazole units. In another embodiment, the invention provides new imidazole compounds usable as monomers to form the polymers. In still another embodiment, the invention provides a method for using the polymers as a coupling/activator for synthon synthesis.

REFERENCES:
patent: 2534331 (1950-12-01), Woodward
patent: 3778446 (1973-12-01), Weigert
patent: 3806517 (1974-04-01), Begland
patent: 4097475 (1978-06-01), James
patent: 4220466 (1980-09-01), Patel
patent: 4299939 (1981-11-01), Panzer
patent: 4410706 (1983-10-01), Rothenberg
patent: 4585724 (1986-04-01), Helling
patent: 4600681 (1986-07-01), Bergthaller
patent: 5021540 (1991-06-01), Leone-Bay
patent: 5122563 (1992-06-01), Kaminski
patent: 5523008 (1996-06-01), Boden
patent: 5663126 (1997-09-01), Boden
patent: 5674436 (1997-10-01), Breitenbach
patent: 5677384 (1997-10-01), Detering
patent: 5712408 (1998-01-01), Rasmussen et al.
P.S. Robertson and J. Vaughan, "Derivatives of the Hydrogen Cyanide Tetramer: Structure and Chemistry," (Dept. of Chemistry, University of Canterbury), Jun. 5, 1958, 2691-2693.
Yoshitaka Yamada, Izumi Kumashiro and Tadao Takenishi, "Synthesis of 4,5-Di-and 1,4,5-Trisubstituted Imidazole Derivatives from 4, 5-Dicyanoimidazole," Bulletin of the Chemical Society of Japan, vol. 41, 1237-1240 (1968).
D.S. Donald and O.W. Webster, "Snythesis of Heterocycles from Hydrogen Cyanide Derivatives," Advances in Hererocyclic Chemistry, vol. 41, 6-9 (1987).
Herman F. Mark, Norbert M. Bikales, Charles G. Overberger, Georg Menges, and Jacqueline I. Kroschwitz, Encyclopedia Of Polymer Science And Engineering, vol. 12, "Polyesters to Polypeptide Synthesis," 346-347 (1988).
David S. Allan, Ernest L. Thurber and Paul G. Rasmussen, "Polymers Containing Cyanoimidazole Pendant Groups", Journal of Polymer Science: Part A: Polymer Chemistry, vol. 28, 2475-2483 (1990).
PCT Search Report, Nov. 25, 1997, PCT/US97/14039 (Aug. 8, 1997).
Chemical Abstracts, vol. 82, No. 25, Jun. 23, 1975, Columbus, Ohio, US Abstract No. 170924q.
Chemical Abstracts, vol. 83, No. 24, Dec. 15, 1975, Columbus, Ohio, US, Abstract No. 195237B.; and.
Chemical Abstracts, vol. 126, No. 20, May 19, 1997, Columbus, Ohio, US, Abstract No. 264400v.
Marvin H. Caruthers, "Gene Synthesis Machines: DNA Chemistry and Its Uses," Journal of Chemical Education, vol. 230, Oct. 1985, 281-285.
Marvin H. Caruthers, "Chemical Synthesis of DNA," Concepts in Chemistry, Journal of Chemical Education, vol. 66, No. 7, Jul. 1989, 577-580.
M.D. Matteucci and M.H. Caruthers, "The Synthesis of Oligodeoxypyrimidines on a Polymer Support," Tetrahedron Letters, vol. 21, pp. 719-722, Pergamon Press Ltd, Great Britain (1980).
Rober L. Letsinger and V. Mahadevan, "Stepwise Synthesis of Oligodeoxyribonucleotides on an Insoluble Polymer Support," Journal of the American Chemical Society, 88:22, Nov. 20, 1966, pp. 5319-5324.
Theophyl Eicher and Dieter Lerch, "Zur Reaktionsweise Des 3-Ethoxy-1,2-Diphenyl-Cyclopropenyliukations Mit Bifunktionellen Aromatischen Aminen," Tetrahedron Letters, vol. 21, pp. 3751-3754 (1980).

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