Cyclosporins

Details Cyclosporins Cyclosporins

1995-04-24

1998-06-16

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 2, 530317, 930270, A61K 3813, C07K 764

Patent

active

057670692

ABSTRACT:
Nonimmunosuppressant cyclosporin derivatives having cyclophilin-binding useful in inhibiting HIV-1 replication in treating AIDS and AIDS related disorders.

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Durette et al, Transplantation Proceedings, vol. 44, No. 2, Seyyl. 2 (Apr., 1988) pp. 51-57.
Wenger, Sandorama, (1984), pp. 5-11.
Rosenwirth, et al., Antimicrobial Agents and Chemotherapy 1994, vol. 38, No. 8 pp. 1763-1772.
Billich, et al., Journal of Virology, Apr. 1995, pp. 2451-2461 --vol. 69, No. 4.
Steinkasserer, et al., Journal of Virology, Feb. 1995, pp. 814-824--vol. 69, No. 2.
Thali, et al., Letters to Nature--vol. 372--24 Nov. 1994.

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