Cyclosporin derivatives, their production and pharmaceutical com

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125R, 435 71, A61K 3700, C07C10352, C12P 2104

Patent

active

042884314

ABSTRACT:
Compounds of formula I ##STR1## selected from the group consisting of cyclosporin G, wherein A is ##STR2## dihydrocyclosporin G, wherein A is ##STR3## and isocyclosporin G, wherein A is ##STR4## are useful in treating inflammations and arthritis and as immuno-suppressant agents.

REFERENCES:
patent: 4108985 (1978-08-01), Ruegger et al.
Traber, et al., Chem. Abstr. 87, 1977 80949A.

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