Cyclosporin analogs for the treatment of immunoregulatory...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C530S317000, C530S321000

Reexamination Certificate

active

11201478

ABSTRACT:
Provided are novel cyclosporin analogs, methods for their production, and their use for treating immunoregulatory and respiratory diseases, disorders, and conditions.

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S.R. Vippagunta, et al. Adv. Drug Delivery Rev. (2001) 48, pp. 3-26.
Vickers, et al. “Human and Rate Lung Biotransformation of Cyclosporin A and its Derivatives Using Slices and Bronchial Epithelial Cells”; Drug Metabolism and Disposition; pp. 873-880; 1997; vol. 25, No. 7; US.
Tsvetelina, et al. “Synthesis and Biological Evaluation of Novel Cyclosporin A Analogues: Potential Soft Drugs for the Treatment of Autoimmune Diseases”; Journal of Medicinal Chemistry, American Chemical Society; pp. 674-676; Jan. 29, 2003; vol. 46, No. 5.

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