Cyclopropylmethylamine derivatives

Details Cyclopropylmethylamine derivatives Cyclopropylmethylamine derivatives

1975-08-15

1978-08-29

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260456P, 260459A, 2605011, 260558R, 260649F, 260649R, 424316, 424330, C07C 8732

Patent

active

041103769

ABSTRACT:
Novel cyclopropylmethylamine compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen or halogen and R.sup.3 is hydrogen or methyl, and their non-toxic salts, which possess various useful pharmacological activities and can be produced by reduction of the corresponding compounds of the formula: ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are each as defined above or their non-toxic salts, or by condensation of the corresponding compounds of the formula: ##STR3## wherein R.sup.1 and R.sup.2 are each defined above, and X is a conventional interchangeable group such as halogen or sulfonyloxy with methylamine or dimethylamine.

REFERENCES:
patent: 3065230 (1962-11-01), Baltzly et al.
patent: 3449427 (1969-06-01), Kaiser et al.
patent: 3462491 (1969-08-01), Kaiser et al.
patent: 3646146 (1972-02-01), Teslino et al.
patent: 3941833 (1976-03-01), Gognaco
Zirkle et al., "Journal Med. Chem.", vol. 5, pp. 1270-1272 (1962).

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