Cyclopropylamines as pharmaceuticals

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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260307R, A01N 922, A01N 928

Patent

active

039884643

ABSTRACT:
The present invention relates to cyclopropylmethyl amines substituted by a heterocyclic radical.
More particularly the heterocyclic radical is a nitrogen containing ring with 5, 6 or 7 links interrupted by another hetero atom selected from the group consisting of oxygen, sulphur and imino--NH--
The invention also relates to the acid addition salts thereof with physiologically compatible mineral or organic acids.
The invention extends to the processes for making them and the intermediates produced hereto.
The invention also includes the pharmaceutical compositions incorporating as active ingredient at least one compound of the invention with an inert carrier.
The compounds have therapeutic utility namely on the cardio-vascular diseases and on the neuro-psychological disturbances.

REFERENCES:
patent: 3626067 (1971-12-01), Harvey
Chem. Abst. 59, 7533(f)(1963)-"N-Substituted--2-aminooxazolines".
Chem. Abst. 71 101842(x)(1969)-"2(cycloalkylamino)-2-oxazolines" Hiltmann et al.
Chem. Abst. 65 13681(e)(1966)-"Synthesis of -oxazolinyl-2-amines-isothiocyanates"-Pfeil et al.

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