Cyclopropyl substituted polyenes

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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Details

424305, 424320, 560118, 562500, 564188, C07C 6118, C07C 6974, A61K 3119, A61K 31215

Patent

active

044316690

ABSTRACT:
There is disclosed certain cyclopropyl substituted polyenes useful for treating dermatoses such as acne, psoriasis and epithelial cancers.

REFERENCES:
patent: 3950418 (1976-04-01), Bollag et al.
patent: 4126698 (1978-11-01), Gander et al.
patent: 4190594 (1980-02-01), Gander et al.
patent: 4304787 (1981-12-01), Gander et al.
Journal of Medicinal Chemistry, vol. 25, No. 11, pp. 1269-1277 (1982), Pawson et al., "Retinoids at the Threshold: Their Biological Significance and Therapeutic Potential".

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