Cyclopropyl derivatives as NK3 receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S223200, C514S226500, C514S230500, C514S252130, C514S278000, C544S048000, C544S070000, C544S386000, C544S392000, C544S393000, C544S398000, C546S016000, C546S017000, C546S019000, C546S020000

Reexamination Certificate

active

07834008

ABSTRACT:
The present invention relates to cyclopropyl derivatives of formula (I) and salt thereof. These compounds are NK3 receptor antagonists and may therefore be useful for treatment of diseases where the NK3 receptor is implicated, e.g. psychotic disorders.

REFERENCES:
patent: 4478836 (1984-10-01), Mouzin et al.
patent: 5434158 (1995-07-01), Shah et al.
patent: 0068999 (1983-01-01), None
patent: 0673928 (1995-09-01), None
patent: WO 97/10211 (1997-03-01), None
patent: WO 03/051869 (2003-06-01), None
Bonnaud, B. et al. (1987) “1-Aryl-2-(aminomethyl)cyclopropancarboxylic acid derivatives. A new series of potential antidepreassants”, Journal of Medicinal Chemistry; 30(2): 318-325.

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