Cyclopropyl derivative lipoxygenase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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Details

564 52, 546300, 546332, A61K 3117, C07C27510

Patent

active

050378538

ABSTRACT:
Certain carbocyclic aryl- and heterocyclic aryl-substituted cyclopropyl N-hydroxyureas, N-hydoroxycarboxamides, and N-acyl-N-hydroxyamides inhibit 5- and/or 12-lipoxygenase and are useful in the treatment of inflammatory disease states.

REFERENCES:
patent: 4724235 (1988-02-01), Shanklin et al.

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