Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1982-07-26
1984-04-10
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
424346, 424353, A01N 4336, A61K 3140, A01N 2904
Patent
active
044421192
ABSTRACT:
Estrogenic cyclopropyl analogs, when administered to a female subject, function as anti-fertility agents to prevent pregnancy in the subject. Further, the estrogenic cyclopropyl analogs may be used as estrogenic agents to produce an estrogenic response in a female subject. The estrogenic cyclopropyl analogs useful as estrogenic agents have the general structure: ##STR1## wherein: X is a halogen or hydrogen atom:
REFERENCES:
Magarian et al., "2-Chloro-1-phenylindene from 1,1-Dichloro-trans-2,3-diphenylcyclopropane", Jour. Pharm. Sciences, (1972), vol. 61, pp. 1216-1219.
Magarian et al., "Synthesis of Cyclopropyl Analogs of Stilbene and Stilbenediol as Possible Antiestrogens", Jour. Pharm. Sciences, (1975), vol. 64, No. 10, pp. 1626-1632.
Hausser et al., "Solvolysis of Cyclopropyl Halides, III, 2,3-Diphenylcyclopropyl Chlorides", J. Org. Chem., 37:4087-4090 (1972).
Magarian Robert A.
Pento Joseph T.
Roberts Elbert L.
The Board of Regents for the University of Oklahoma
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