Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-25
1994-07-12
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514300, 514311, 514330, 514331, 514354, 514355, 514356, 514406, 514427, 514436, 514443, 514469, 514471, 514487, 514489, 514531, 514568, 514580, 514601, 514604, 514605, 514616, 514619, 514626, 544335, 544316, 546122, 546168, 546169, 546170, 546173, 546234, 546235, 546261, 546262, 546263, 546265, 548561, 5483741, 5483335, 549 58, 549 77, 549467, 549496, 560 39, 560 41, 560125, 562448, 562450, 562506, 564 46, 564 59, 564 91, 564152, 564155, 564164, 564168, A61K 3116, A61K 31165, C07C23720, C07C23722
Patent
active
053289099
ABSTRACT:
A novel cyclopropenone derivative (I) which possesses a potent inhibitory activity against thiol protease such as papain, cathepsin B, cathepsin H, cathepsin L, calpain or the like with excellent properties regarding oral absorbance, tissue transference and cell membrane permeability, and are clinically useful in the treatment of various diseases such as muscular dystrophy, amyotrophy. Also provided are a process for producing the compound (I) and a pharmaceutical composition containing the same.
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Ando Ryoichi
Morinaka Yasuhiro
Takahashi Chizuko
Tamao Yoshikuni
Tobe Akihiro
Mitsubishi Kasei Corporation
O'Sullivan P.
Robinson Allen J.
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