Cyclopropane carboxylic acid ester derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260465D, 424274, 424285, 424305, 424308, 548513, 549462, 549467, 549479, 549491, 549501, 560 65, 560 73, 560118, 560124, A01N 3734, A01N 5300, C07C 69757, C07C12175

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044316682

ABSTRACT:
Cyclopropane carboxylic acid ester derivatives and optical and geometrical isomers thereof expressed by the general formula: ##STR1## wherein R.sub.1 represents hydrogen atom or methyl group, R.sub.2 represents alkyl group, alkenyl group, haloalkyl group, haloalkenyl group having 1-6 carbon atoms and a group selected from the groups of the general formulae (II), (III) and (IV): ##STR2## in which n is an integer of 2-5, R.sub.4 represents methyl group, chlorine atom or methoxy group, and R.sub.3 represents a group selected from the groups of the general formulae (V), (VI), (VII), (VIII), (IX) and (X): ##STR3## in which X represents oxygen atom or vinylene group, R.sub.5 represents allyl group, propargyl group, benzyl group, phenoxy group or 2,2-dichlorovinyloxy group, R.sub.6 represents hydrogen atom, methyl group or halogen atom, R.sub.7 represents hydrogen atom, cyano group, ethynyl group or trifluoromethyl group and m is an integer of 1-2, R.sub.8 represents allyl group or alkadienyl group, Y represents oxygen atom or methylene group, R.sub.9 represents hydrogen atom, methyl group, allyl group or halogen atom and R.sub.10 represents methyl group or halogen atom.

REFERENCES:
patent: 3847944 (1974-11-01), Ohno et al.
Wenbert et al., Chemical Abstracts, vol. 74, 42507d, (1971).
Smejkal et al., Chemical Abstract, vol. 54, 24436-24437, (1960).
Julia et al., Chemical Abstracts, vol. 50, 5228-5229, (1956).
Julia et al., Bull. Soc. Chim., France, pp. 734-742, (1966).

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