Cyclopeptides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 9, 514 17, 530317, 530330, A61K 3808, A61K 3812, C07K 764

Patent

active

057054819

ABSTRACT:
The invention relates to novel cyclopeptides of the formula I

REFERENCES:
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patent: 4713367 (1987-12-01), Sisto et al.
patent: 4816449 (1989-03-01), Hahn
Rudinger, j. (Jun. 1976). Peptide Hormones. (ed. J. A. Parsons). University Park Press. Baltimore. pp. 1-7.
Chemical Abstracts, vol. 114, No. 9 (Mar. 4, 1991), p. 481, No. 114:79202w.
Chemical Abstracts, vol. 110, No. 17 (Apr. 24, 1989), p. 312, No. 110:150020k.
Chemical Abstracts, vol. 107, No. 1 (Jul. 6, 1987), p. 476, No. 107:5066p.
Chemical Abstracts, Vo. 103, No. 25 (Dec. 23, 1985), p. 627. No. 103:212136u.
Aumailley et al., "Arg-Gly-Asp constrained within cyclic per strong and selective inhibitors of cell adhesion to vitro fragment P1," FEBS, vol. 291, No. 1, pp. 50-54.
Neubert et al., "Synthese cyclischer und cyclisch-verzweigter Tachykinin-Teilsequenzen," Pharmazie 40 (1985), H.8, pp. 532-535. Only the abstract was considered. (see p. 532).
Smith et al., "Interaction of Integrins .alpha..sub.v .beta..sub.3 and Glycoprotein IIb-IIIa with Fibrinogen," The Journal of Biological Chemistry, 1990, pp. 12267-12271.

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