Cyclopeptide derivatives

Details Cyclopeptide derivatives Cyclopeptide derivatives

2006-02-07

2006-02-07

Lukton, David (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

4 to 5 amino acid residues in defined sequence

C530S329000, C530S331000, C530S317000, C530S345000, C514S011400, C514S017400, C514S018700, C424S422000

Reexamination Certificate

active

06995238

ABSTRACT:
Disclosed herein is a process for promoting the integration of a biocompatible device or implant into a tissue of a subject. The process comprises covalently bonding to the surface of the device or implant a compound of the formula Iin-line-formulae description="In-line Formulae" end="lead"?R-Q-X  Iin-line-formulae description="In-line Formulae" end="tail"?wherein R is cyclo-(Arg-Gly-Asp-Z), and wherein Q, X and Z are as defined herein.

REFERENCES:
patent: 5939383 (1999-08-01), Remacle et al.
patent: 6566491 (2003-05-01), Jonczyk et al.
patent: 0 844 252 (1998-05-01), None
Hafdi, Z. (Cell adhesion and communication 7 (6) 441-51, 2000).
Philp, N. J. (Investigative ophthalmology & visual science 28 (8) 1275-80, 1987).
Rosengren A (Journal of Materials Science. Materials in Medicine 9 (7) 415-20, 1998).
Taylor M (Journal of bone and joint surgery. British vol. 79 (2) 181-2, 1997).
Koutsonikos A. (Annals of the Royal Australasian College of Dental Surgeons 14 75-80, 1998).
Duyck J. (Clinical oral investigations 2 (3) 102-14, 1998).
Steenberghe D (Advances in dental research 13 130-5, 1999).
Ziats N. P. (Biomaterials 9, 5-13, 1988).
Zhao, Q. (J Biomed Mater Res 25, 177-183 1991).
Saadoun A P (Practical periodontics and aesthetic dentistry: PPAD 5 (6) 11-20, 1993).
Bauman G. R. (International journal of oral & maxillofacial implants 7 (3) 330-7, 1992).
Bauer T W (Skeletal radiology 28 (9) 483-97, 1999).
Rosch R (European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 35 (3) 161-6, 2003).
Esposito M (Journal of materials science. Materials in medicine 8 (12) 843-7, 1997).
Dechantsreiter (J Med Chem. 42, 3033, 1999).
Haubner (J Am Chem Soc 118, 7881, 1996).
Schaffner P., Journal of Materials Science. Materials in Medicine 10 (12), 837-9, 1999
search report for WO 99/31126, issued Jun. 1999.
Abstract of DE 4310643, Oct. 1997.
Abstract of DE 19725368, Dec. 1998.
D. Delforge, et al., “Automated Solid-Phase Synthesis of Cyclic Peptides Bearing a Side-Chain Tail Designed for Designed for Subsequent Chemical Grafting”, Analytical Biochemistry 242, (1996), pgs. 180-186.
D. Delforge, et al., “Solid-phase synthesis of tailed cyclic peptides: The use of α-allyl-protected aspartic acid leads to aspartimide and tetramethylguanidnium formation”, Letters in Peptide Science, 3, (1996), pgs. 89-97.
B. Elmengaard, et al., “In vivo study of the effect of RGD Treatment on bone ongrowth on press-fit titanium alloy implants”, Biomaterials 26, (2005), pgs. 3521-3526.
P. Schaffner, et al., “induced tissue intregration of bone implants by coating with bone selective RGD-peptides in vitro and in vivo studies”, Kluwer Academic Publishers, (1999), pgs. 837-839.
Z Hafdi, et al., Distribution of ανβ3m ανβ5 Integrins and the Integrin Associated Protein —IAP (CD47) iin Human Glomerular Diseases, Cell Adhesion and Communication, vol. 7, No. 6, (2000), pgs. 441-451.
D. VanSteenberghe, et al., “Influence of Inflammatory Reactions vs. Occiusal Loading on Peri-implant Marginal Bone level”, advances in Dental Research, (1999), pgs. 130-135.
M. Esposito, et al., “Failure patterns of four osseointegrated oral implant systems”, Journal of Materials Science, (1997), pgs. 843-847.
R. Rosch et al., “Mesh Implants in Hernia Repair”, Mesh Implants in Hernia Repair, Eur. Surg. Res., (2003), pgs. 161-166.
Thomas W. Bauer, et al., , “The pathology of total joint arthroplasty. II. Mechanisms of implants faliure”, Skeletal Radiol, 28, (1999), pgs. 483-497.
Geoffrey R. Bauman, et al., “Plaque-induced Inflammation Around implants”, Int. J Oral Maxillofac Implants, vol. 7, No. 3, (1992), pgs. 330-337.
AndrèSaadoun, Microbial Infections and Occiusal Overload: Causes of Failure in Osseointegrated implants, PPAD, (1993), pgs. 11-20.
Q. Zhao, “Foreign-body giant cells and polyurethane biostability: In vivo correlation of cell adhesion and surface cracking”, Journal of Biomedical Materials Research, vol. 25, (1991), pgs 177-183.
Nicholas P. Ziats, “In vitro and in vivo Interactions of cells with biomaterials”, Biomaterials, (1888), vol. 9, pgs. 5-13.
J. Buyck, et al., “Failure of oral implants: aetiology, symptoms and Influencing factors”, Clin. Oral Invest (1998), pgs. 102-114.
A. Koutsonikos, “Implants: Success and Failure”, Annals of the Royal Australasian College of Dental Surgeons , (1998), pgs. 75-80.
M. Taylor, “Fatigue failure of cancellous bone: a possible cause of Implant migration and loosening”, Journal of bone and joint Surgery, Pgs. 181-182.
Nancy J. Philp, et al., “Polarized Distribution of Integrin and Fibronectin in Retinal Pigment Epithelium”, Investigative Opthalmology & Visual Science, (1997), pgs. 1275-1280.

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