Cyclopentenone derivatives for cancer therapy

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C564S248000, C562S504000

Reexamination Certificate

active

10309754

ABSTRACT:
The invention relates to the use of derivatives of cyclopentenone for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention relates more specifically to the use of derivatives of cyclopentenone for the inhibition and/or prevention of cancer of the colon, pancreas, larynx, ovary, duodenum, kidney, oral cavity, prostate, lung, endothelial cells and leukemias.

REFERENCES:
Challener et al., Journal of the American Chemical Society (1993), 115(4), 1359-76.
Melchiorre et al. European Journal of Medicinal Chemistry (1975), 10(6), 623-7, Chemical Abstract online citation.
Shoppee et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1972), (18), 2271-6 Chemical Abstracts online citation.
Chemical Abstracts online citation [retrieved Mar. 30, 2006] from STN, Columbus, OH, USA, Abstract No. 1951:11128.

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