Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1996-04-08
1997-08-19
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
546 22, 549 6, 549218, 558190, 558191, 558194, 558195, 558198, 562 10, 514 89, 514 95, 514 99, 514114, 514119, 514120, 514127, 514129, A61K 3166, C07F 942, C07F 944
Patent
active
056588976
ABSTRACT:
The present invention relates to cyclopentane (or cyclopentane) heptanoic or cyclopentane (or cyclopentene) heptenoic acid, 2-hydrocarbyl phosphinyloxyalkyl or phosphonamidoalkyl, 1-esters, and derivatives thereof, useful as therapeutic agents. In particular, the therapeutic agents of this invention are useful as ocular hypotensives.
REFERENCES:
patent: 4599353 (1986-07-01), Bito
patent: 4994274 (1991-02-01), Chan et al.
patent: 5028624 (1991-07-01), Chan et al.
patent: 5034413 (1991-07-01), Chan et al.
patent: 5288754 (1994-02-01), Woodward et al.
Bito, L.Z., "Prostaglandins, Old Concepts and New Perspectives," Arch Oph., vol. 105, Aug. 1987 pp. 1036-1039.
Bito, L.Z., "Prostaglandins and Related Compounds as Potential Ocular Therapeutic Agents", Biological Protection with Prostaglandins (Cohen, M.M., ed., Boc Raton, FL, CRC Press Inc., 1985, pp. 231-252.
Bito, L.Z., "Prostaglandins, Other Eicosanoids, and Their Derivatives as Potential Antiglaucoma Agents", Applied Pharmacology in the Medical Treatment of Glaucoma, 1984, pp. 477-505.
Nilsson, Siv F.E., et al, "PGF2a Increases Uveoscleral Outflow", ARVO Abstract,, Invest. Ophthalmol. Vis. Sci. 28 (suppl), 1987, p. 284.
Starr, M.S., "Further Studies on the Effect of Prostaglandin on Intraocular Pressure in the Rabbit", Exp. Eye Res., 1971, pp. 170-177.
Siebold et al, "Esterified prostaglandin shows `potent` promise", Prodrug 5, 1989, pp. 3-4.
Allergan
Ambrose Michael G.
Baran Robert J.
Lambert Howard R.
Richter Johann
LandOfFree
Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid,, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1104883