Cyclopentane derivatives

Details Cyclopentane derivatives Cyclopentane derivatives

1974-11-12

1977-07-19

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603409, 260488R, 260514D, 424305, 424317, C07C17700

Patent

active

040368726

ABSTRACT:
Cyclopentane derivatives of the formula: ##STR1## wherein R.sup.1 represents alkyl of 1 through 4 carbon atoms, R.sup.2 represents hydrogen or alkyl of 1 through 3 carbon atoms, R.sup.3 represents alkoxy of 3 through 6 carbon atoms, or alkoxyalkyl in which alkoxy and alkyl moieties each contain 1 through 4 carbon atoms, R.sup.4 represents hydrogen or alkyl of 1 through 12 carbon atoms, R.sup.5 represents hydrogen or alkyl of 1 through 4 carbon atoms or a carboxylic acyl group, A represents carbonyl or a group --CH(OR.sup.5)-- wherein R.sup.5 is as hereinbefore defined, and X represents ethylene or trans-vinylene, possess pharmacological properties, for example the production of hypotension, broncodilation, inhibition of gastric acid secretion, and stimulation of uterine contraction.

REFERENCES:
patent: 3816393 (1974-06-01), Hayashi et al.
Karim, Prostaglandins pp. 313-315 (1972).

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