Cyclopenta[d]pyrimidine derivatives and use as antidepressants

Details Cyclopenta[d]pyrimidine derivatives and use as antidepressants Cyclopenta[d]pyrimidine derivatives and use as antidepressants

1986-03-06

1988-06-07

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544253, A61K 31505, C07D23970

Patent

active

047497041

ABSTRACT:
Compounds of formula (I): ##STR1## (wherein R.sup.1 and R.sup.2 are hydroxy, alkoxy, aryloxy or acyloxy or R.sup.2 is hydrogen, R.sup.3 is hydrogen or alkyl and R.sup.4 and R.sup.5 are hydrogen or various organic substituents) have valuable antidepressant activity and may be used in the treatment of mental depression.

REFERENCES:
patent: 3915976 (1975-10-01), Salmond
patent: 3980650 (1976-09-01), Nauta
patent: 4435402 (1984-03-01), Tsuji et al.
patent: 4450162 (1984-05-01), Kamioka et al.

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