Cyclopenta (C) pyrrole derivatives

Details Cyclopenta (C) pyrrole derivatives Cyclopenta (C) pyrrole derivatives

1977-02-25

1978-11-21

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

544122, 544120, 544114, 544130, 544126, 544182, 544238, 544277, 544331, 544128, 544139, 544140, 544132, 544327, 544133, 544328, 544135, 544134, 544137, 544 80, 260304D, 544112, 544118, 260304H, 260305, 260307D, 260308D, 260308R, 2603067T, 2603068R, 2603068D, 260315, 26032627, 544143, 548327, 548336, 548371, 548374, 546106, 546143, 546187, 546194, 546200, 546199, 546198, 546271, 546272, C07D20902, C07D40306

Patent

active

041266200

ABSTRACT:
2,4,5,6-Tetrahydrocyclopenta[c]pyrrole-4-carboxamide and 4-thiocarboxamide derivatives useful as antisecretory and anti-ulcer agents are prepared by hydrolysis or thiohydrolysis of the corresponding 2,4,5,6-tetrahydrocyclopenta[c]pyrrole-4-carbonitriles or, in the case of the thiocarboxamides, by reaction of the 4-carboxamide with phosphorus pentasulfide.

REFERENCES:
patent: 3696117 (1972-10-01), Beregi et al.
patent: 3928380 (1975-12-01), Bell et al.
patent: 3972994 (1976-08-01), Beregi et al.
patent: 4008250 (1977-09-01), Bell et al.
Volz et al., Tet. Letters., vol. 47, p. 4111-4114, (1969).
Berger et al., J. Org. Chem., vol. 35, p. 3122, (1970).
Jain et al., Chem. Abs., vol. 53:12275i, (1959).

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