Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-03-06
1985-12-10
Fan, Jane T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
562503, 549311, 549465, C07D30793
Patent
active
045581401
ABSTRACT:
New optically active intermediates and processes thereto are provided for use in synthesizing therapeutically active prostaglandins of the formula: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; from a compound of the formula: ##STR2## wherein R.sup.1 is as above and R.sup.2 is hydrogen or a carboxy blocking group convertible to an acid by hydrolysis.
REFERENCES:
patent: 4044005 (1977-08-01), Kienzle et al.
Overman et al., Tet. Letters, 4, 321-324, (1979).
Vasil'eva et al., J. Gen. Chem. USSR 52, 2346-47, (1982).
Grieco et al., J. Am. Chem. Soc. 102, 7587-88, (1980).
Grieco et al., J. Org. Chem. 46, 5005-07, (1981).
Coffen David L.
Holland George W.
Rosen Perry
Wong Frederick
Fan Jane T.
Hoffmann-La Roche Inc.
Johnston George W.
Leon Bernard S.
Saxe Jon S.
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