Cyclopamine analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C546S115000, C549S331000, C549S345000

Reexamination Certificate

active

07812164

ABSTRACT:
The invention provides novel derivatives of cyclopamine having the following formula:

REFERENCES:
patent: 6238876 (2001-05-01), Altaba
patent: 6291516 (2001-09-01), Dudek et al.
patent: 6432970 (2002-08-01), Beachy et al.
patent: 6867216 (2005-03-01), Beachy et al.
patent: 7230004 (2006-04-01), Adams et al.
patent: 7098196 (2006-08-01), Beachy et al.
patent: 7291626 (2007-11-01), Beachy et al.
patent: 7407967 (2008-08-01), Adams et al.
patent: 2003/0114393 (2003-06-01), Liscovitch et al.
patent: 2003/0162870 (2003-08-01), Kimura et al.
patent: 2004/0072913 (2004-04-01), Tas et al.
patent: 2004/0072914 (2004-04-01), Tas et al.
patent: 2004/0110663 (2004-06-01), Dudek et al.
patent: 2004/0126359 (2004-07-01), Lamb et al.
patent: 2004/0127474 (2004-07-01), Dudek et al.
patent: 2006/0094660 (2006-05-01), Thomson
patent: 2006/0128639 (2006-06-01), Beachy
patent: 2006/0142245 (2006-06-01), Beachy et al.
patent: 2007/0009530 (2007-01-01), Altaba
patent: 2007/0231828 (2007-10-01), Beachy et al.
patent: 2007/0281040 (2007-12-01), Weichselbaum et al.
patent: 2008/0019961 (2008-01-01), Wicha et al.
patent: 2008/0057071 (2008-03-01), Watkins et al.
patent: 2008/0058298 (2008-03-01), Beachy et al.
patent: 2008/0095761 (2008-04-01), Beachy et al.
patent: 2008/0118493 (2008-05-01), Beachy et al.
patent: WO-95/18856 (1995-07-01), None
patent: WO-96/17924 (1996-06-01), None
patent: WO-00/41545 (2000-07-01), None
patent: WO-01/27135 (2001-04-01), None
patent: WO-01/49279 (2001-07-01), None
patent: WO-02/30462 (2002-04-01), None
patent: WO-2005/013800 (2005-02-01), None
patent: WO-2005/032343 (2005-04-01), None
patent: WO-2005/042700 (2005-05-01), None
patent: WO-2006/026430 (2006-03-01), None
patent: WO-2007/123511 (2007-11-01), None
patent: WO-2008/083248 (2008-07-01), None
patent: WO-2008/083252 (2008-07-01), None
patent: WO-2008/089123 (2008-07-01), None
International Search Report for PCT/US07/88990, mailed on Aug. 1, 2008, 2 pages.
Written Opinion of the International Searching Authority for PCT/US07/88990, mailed on Aug. 1, 2008, 8 pages.
International Search Report for PCT/US07/88995, mailed on Aug. 1, 2008, 2 pages.
Written Opinion of the International Searching Authority for PCT/US07/88995, mailed on Aug. 1, 2008, 6 pages.
Voituriez et al., Adv. Synth. Catal. (2006) 348:2363-2370.
Alexandre et al., Genes and Development (1996) 10:2003-2013.
Bale and Yu, Human Molecular Genetics (2001) 10:757-762.
Belloni et al., Nature Genetics (1996) 14:353-356.
Berge et al, Journal of Pharmaceutical Sciences (1977) 66:1-19.
Berman et al., Nature (2003) 425:846-851.
Berman et al., Science (2002) 297:1559-1561.
Chen et al., Genes and Development (2002) 16:2743-2748.
Cooper et al., Science (1998) 280:1603-1607.
Fan et al., Endocrinology (2004) 145:3961-3970.
International Search Report for PCT/US05/30406, published as WO/2006/026430, mailed on Apr. 4, 2006, 2 pages.
Karhadker et al., Nature (2004) 431:707-712.
Kitajima et al., Heterocycles (1981) 15:791-796.
Kubo et al., Cancer Research (2004) 64:6071-6074.
Lee et al., Journal of Agricultural and Food Chemistry (2003) 51(3):582-586.
Lewis and Veltmaat, Journal of Mammary Gland Biology and Neoplasia (2004) 2:165-181.
Ma et al., Carcinogenesis (2005) 10:1698-1705.
Nakamura et al., Biochemical and Biophysical Research Communications (1997) 237:465-469.
Patil et al., Cancer Biology & Therapy (2006) 5:111-117.
Peacock et al., PNAS USA (2007) 104:4048-4053.
Pietsch et al, Cancer Research (1997) 57:2085-2088.
Quirk et al., Cold Spring Harbor Symposium Quant. Biol. (1997) 62:217-226.
Rahman et al., Phytochemistry (1991) 1:368-370.
Reifenberger et al., Cancer Research (1998) 58:1798-1803.
Sheng et al., Molecular Cancer (2004) 3:29-42.
Sicklick et al, Carcinogenesis (2006) 27:748-757.
Supplementary Partial European Search Report for EP 05791140.6, mailed Nov. 26, 2007, 7 pages.
Tas and Avci, Dermatology (2004) 209:126-131.
Thayer et al., Nature (2003) 425:851-856.
Van Der Horst et al., Bone (2003) 33:899-910.
Watkins et al., Nature (2003) 422:313-317.
Williams et al., PNAS USA (2003) 100:4616-4621.
Xie et al., Nature (1998) 391:90-92.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cyclopamine analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclopamine analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclopamine analogs will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4153040

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.