Cyclooxygenase-2 inhibitor compositions having rapid onset...

Details Cyclooxygenase-2 inhibitor compositions having rapid onset... Cyclooxygenase-2 inhibitor compositions having rapid onset...

2007-02-06

2007-02-06

Azpuru, Carlos A. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S489000

Reexamination Certificate

active

10031898

ABSTRACT:
Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility in a therapeutically effective amount, wherein the drug is present in the form of solid particle, about 25% to 100% by weight of which are smaller than 1 μm. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired.

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