Cyclohexylbenzamide derivatives, their preparations and their us

Details Cyclohexylbenzamide derivatives, their preparations and their us Cyclohexylbenzamide derivatives, their preparations and their us

1992-03-25

1993-12-28

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514320, 514327, 546196, 546221, 546234, A61K 31445, C07D40508, C07D21132

Patent

active

052739830

ABSTRACT:
Novel N-cyclohexylbenzamide derivatives of formula: ##STR1## where R.sub.1 represents an alkoxy radical capable of cyclizing with the aromatic ring;
R.sub.2, R.sub.3 and R.sub.4 each independently represent hydrogen, a halogen or an alkoxy, amino, alkylamino or alkyl-carbonylamino group, and
Z represents a differently substituted piperidinyl group; and their addition salts with pharmaceutically acceptable acids.
The compounds of formula I are powerful gastrointestinal motility stimulants.

REFERENCES:
Ellis and Lee "Esters and Amides from Mannich Ketanes" J. Med. Chem. 10 (1) 130-131 (1967).

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