Cyclohexyl-triethylenetetraamine hexacetic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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424 11, C07C22900

Patent

active

050896636

ABSTRACT:
The present invention relates to new rigid chelating structures, to methods for preparing these materials, and to their use in preparing radiometal labeled immunoconjugates. These new chelates include cyclohexyl EDTA monohydride, the trans forms of cyclohexyl DTPA and TTHA, and derivatives of these cyclohexyl polyaminocarboxylate materials.

REFERENCES:
patent: 4352751 (1982-10-01), Wieder et al.
patent: 4707440 (1987-11-01), Stavrianopoulos
Takeshita, et al., JAOCS, 59, No. 2 (Feb. 1982).

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