Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1991-04-02
1992-02-18
Maples, John S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
424 11, C07C22900
Patent
active
050896636
ABSTRACT:
The present invention relates to new rigid chelating structures, to methods for preparing these materials, and to their use in preparing radiometal labeled immunoconjugates. These new chelates include cyclohexyl EDTA monohydride, the trans forms of cyclohexyl DTPA and TTHA, and derivatives of these cyclohexyl polyaminocarboxylate materials.
REFERENCES:
patent: 4352751 (1982-10-01), Wieder et al.
patent: 4707440 (1987-11-01), Stavrianopoulos
Takeshita, et al., JAOCS, 59, No. 2 (Feb. 1982).
Gestin Jean-Francois
Mease Ronnie C.
Srivastava Suresh C.
Associated Universities Inc.
Bogosian Margaret C.
Maples John S.
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