Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Reexamination Certificate
2007-05-11
2008-03-11
Witherspoon, Sikarl A. (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
C514S690000
Reexamination Certificate
active
07342137
ABSTRACT:
The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorate, in particular to 4-hydroxy-2,3 -dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, and its use in tumor growth inhibition. The compound of the invention, which has never been discovered in Antrodia camphorate, can be applied in inhibiting the growth of cancer cells, such as breast cancer, hepatic cancer and prostate cancer; and be used as a pharmaceutical composition to inhibit the tumor growth; or further be applied in prevention of heart and blood vessel disease or dietary supplements for health needs through its antioxidant activity.
REFERENCES:
I-Hwa Cherng et al., Three New Triterpenoids from Antrodia Cinnamomea, Journal, Mar. 1995, vol. 58 No. 3, pp. 365-371, Journal of Natural Products.
Chung-Hsiung Chen et al., New Steroid Acids from Antrodia Cinnamomea a Fungal Parasite of Cinnamomum Micranthum, Journal, Nov. 1995, vol. 58 No. 11, pp. 1655-1661, Journal of Natural Products.
Hung-Chen Chiang et al., A sesquiterpene lactone, phenyl compounds from Antrodia cinnamomea, Journal, Jun. 1995, vol. 29 No. 2, pp. 613-616, Elsevier Science Ltd.
Shu-Wei Yang et al., Steriods and triterpenoids of Antodia cinnamomea-a fungus parasitic on Cinnamomum micranthus, Journal, Mar. 1996, vol. 41 No. 5, pp. 1389-1392, Elsevier Science Ltd.
I-Hwa Cherng et al., Triterpenoids form Antrodia cinnamomea, Journal, Jan. 1996, vol. 41 No. 1, pp. 263-267, Elsevier Science Ltd.
Chang Chun-Chou
Fok Ka-Hang
Huang Chun-Hung
Kuo Mao-Tien
Li Ya-Ying
Golden Biotechnology Corporation
King Anthony
Witherspoon Sikarl A.
WPAT, P.C.
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