Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1981-01-27
1982-06-22
Helfin, Bernard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
564338, 564171, 560 27, 568647, 568442, 548452, A61K 31135
Patent
active
043362680
ABSTRACT:
Cyclohexenes of the formula ##STR1## wherein R.sup.1 is hydroxy or lower alkoxy; n is 1 or 2; R.sup.2 is lower alkyl; and R.sup.3 is hydrogen, lower alkyl, lower alkenyl or lower cycloalkylmethyl, and their pharmaceutically acceptable acid addition salts are disclosed. The compounds of formula I have analgesic activity and are useful for the control of pains.
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Psotta et al., Tetrahedron, vol. 35, (1979), 255-257.
Schwenker et al., Archiv. der Pharmazie, vol. 301, (1968), 592-595.
Bruderer Hans
Fischli Albert E.
Pfister Rudolf
Helfin Bernard
Hoffmann-La Roche Inc.
Isgro William G.
Leon Bernard S.
Saxe Jon S.
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