Cyclohexanone-5,6-benzo analogues of prostaglandin

Details Cyclohexanone-5,6-benzo analogues of prostaglandin Cyclohexanone-5,6-benzo analogues of prostaglandin

1977-04-20

1978-07-11

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 55, 260456P, 260465F, 260515R, 260520R, 424308, 424317, C07C17700, C07C 6976

Patent

active

041003527

ABSTRACT:
Disclosed are prostaglandin analogues having the structural formula, ##STR1## in which: T is selected from the group consisting of carboxyl, alkoxycarbonyl or cyano;
M is selected from the group consisting of carbonyl, R-hydroxymethylene or S-hydroxymethylene;
L is selected from the group consisting of methylene or methine, provided L is methine only if J is methine;
J is selected from the group consisting of methylene, ethylene, R-hydroxymethylene, S-hydroxymethylene or methine, provided J is methine only if L is methine;
W is selected from the group consisting of ##STR2## T.sub.1 and T.sub.2 are attached to adjacent carbon atoms; T.sub.1 is selected from the group consisting of hydrogen or phenyl, provided T.sub.1 is phenyl only if T.sub.2 is lower alkyl;
T.sub.2 is selected from the group consisting of n-pentyl or lower alkyl, provided T.sub.2 is lower alkyl only if T.sub.1 is phenyl;
Or T.sub.1 and T.sub.2 are joined together to form an alkylene group of 4 or 6 carbon atoms. Also disclosed are methods for preparing such prostaglandin analogues.

REFERENCES:
Derwent Abstr. 08596x/05, NL 7508-301, 14-01-76.
Derwent Abstr. 01790x/01, U.S. 3928-418, 23-12-75.
Derwent Abstr. 66750t-b, DT2209990-Q, 21-09-72.

Affiliated with

Also associated with

Rating

Cyclohexanone-5,6-benzo analogues of prostaglandin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclohexanone-5,6-benzo analogues of prostaglandin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclohexanone-5,6-benzo analogues of prostaglandin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-263276