Cyclohexa-2,5-diene-1-thiones

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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26023955D, 2603972, 26039745, 2603975, A61K 3158

Patent

active

040113167

ABSTRACT:
Compounds of the general formula ##STR1## are provided wherein the substituents R, which may be the same or are different, represent hydrogen atoms or hydrocarbyl groups and the groups R.sup.1 represent hydrocarbyl groups or adjacent pairs of substituents R, or R and R.sup.1 together with the carbon atoms to which they are attached may constitute a non-aromatic ring structure, said hydrocarbyl groups or ring structure if desired carrying one or more substituents. Preferred compounds include steroid 1,4-diene-3-thiones of the cholestane, androstane, oestrane and pregnane series. Compositions containing these compounds are also provided.

REFERENCES:
bourdon, "Bull. Soc. Chem., France," 1958, pp. 722-725.
Kincle, "Berichte" 93, 1960, pp. 1043-1046.
Djerassi et al. "Jour. Org. Chem." vol. 26 (1961), pp. 4675-4677.

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