Cyclohepta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives

Details Cyclohepta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives Cyclohepta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives

2005-02-22

2005-02-22

Coleman, Brenda (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S555000, C540S556000

Reexamination Certificate

active

06858604

ABSTRACT:
This invention provides compounds of the formula:wherein R1and R2are each, independently, H, alkyl, cycloalkyl, —CH2-cycloalkyl, alkoxy, halogen, fluorinated alkyl, —CN, —NH—SO2-alkyl, —SO2—NH-alkyl, alkyl amide, amino, alkylamino, dialkylamino, fluorinated alkoxy, acyl, or phenoyl or thiophenoyl; R3and R4are each, independently, H, alkyl or cycloalkyl; R5is H or alkyl; R6is H or; and the dashed line indicates an optional double bond; or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions and methods utilizing these compounds for the treatment or prevention of disorders including obsessive-compulsive disorder, depression, anxiety, generalized anxiety disorder, schizophrenia, migraine, sleep disorders, eating disorders, obesity, epilepsy, and spinal cord injury.

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