Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-07-21
1988-10-04
Ramsuer, R. W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548439, 548448, A61K 31405, C07D20986, C07D20988
Patent
active
047756802
ABSTRACT:
Cyclohept[b]indolealkanoic acids and acid derivatives are disclosed. The compounds act as prostaglandin and thromboxane antagonists and are useful in treating asthma, diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea and nephrotoxicity caused by cyclosporin A and as cytoprotective agents.
REFERENCES:
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patent: 3905998 (1975-09-01), Alexander
patent: 3956295 (1976-05-01), Biere et al.
patent: 4009181 (1977-02-01), Berger et al.
patent: 4057559 (1977-11-01), Asselin et al.
patent: 4128560 (1978-05-01), Asselin et al.
Gillard John W.
Girard Yves
Guindon Yvan
Morton Howard E.
Caruso Charles M.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Ramsuer R. W.
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