Cyclohept(B)indolealkanoic acids, pharmaceutical compositions an

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5142328, 514253, 514323, 514381, 544142, 544372, 546200, 548252, 548253, 548439, 548448, A61K 3140, C07D20986, C07D20988

Patent

active

050175971

ABSTRACT:
Cyclohept[b]indolealkanoic acids and acid derivatives are disclosed. The compounds act as prostaglandin and thromboxane antagonists and are useful in treating asthma, diarrhea, hypertension, angina, platelet, aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea and nephrotoxicity caused by cyclosporin A and as cytoprotective agents.

REFERENCES:
patent: 4009181 (1977-02-01), Berger et al.
patent: 4057559 (1977-11-01), Asselin et al.
Perni et al., Chemical Abstracts, vol. 98 (1983), 98: 16537q.

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