Cyclodextrins as suspending agents for pharmaceutical suspension

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514777, 514914, A61K 3156, A61K 4700

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active

055763111

ABSTRACT:
The present invention relates to stable aqueous suspension of drugs suitable for therapeutic administration without requiring solubilization or complexation of those drugs. The suspensions are stabilized with cyclodextrin type suspending agents. Stabilized suspensions of corticosteroids which employ these suspending agents are useful for therapeutic treatment of the eye, ear, or nose.

REFERENCES:
patent: 2861920 (1958-11-01), Dale et al.
patent: 4383992 (1983-05-01), Lipari
patent: 4596795 (1986-06-01), Pitha
patent: 4710495 (1987-12-01), Bodor
patent: 4727064 (1988-02-01), Pitha
patent: 5089482 (1992-02-01), Hermans et al.
CA 117:178175, Alberth et al., 1991.
Remington's Pharmaceutical Sciences, 18th Ed., pp. 1587-1592, 1990.

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