Cyclodextrin-silica composite and a method for the preparation t

Compositions – Preservative agents – Anti-corrosion

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210635, 424469, 424488, 424493, 42721334, 42840224, 435178, 502404, 514963, 514965, A01N 2510, A61K 926, B01J 1300, B01J 1302

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047818581

ABSTRACT:
A mixture of a cyclodextrin and an alkoxy silane compound, e.g., tetraethoxy silane, is admixed with water and an acidic or alkaline catalyst, e.g., acetic acid, to effect ligand exchange and hydrolysis of the alkoxy silane followed by gelation into a gelled mass which is dried and, preferably, leached with water to remove excess of the cyclodextrin. The thus obtained gelled material is a composite having a structure in which the cyclodextrin molecules are incorporated into the matrix of amorphous silica presumably by forming Si-O-C linkages. The composite has characteristics as a combination of the properties of both of the component materials and can expand the applicability of the materials, for example, as a carrier of catalysts and immobilized enzymes, absorbent and adsorbent and so on.

REFERENCES:
patent: 3146252 (1964-08-01), Emblem et al.
patent: 4169069 (1979-09-01), Unger et al.
patent: 4432802 (1984-02-01), Harata et al.
patent: 4539399 (1985-09-01), Armstrong
patent: 4579779 (1986-04-01), Ohno
patent: 4667417 (1987-05-01), Graser et al.

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