Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-04-28
1996-01-23
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 59, 514475, 514777, 514778, A61K 31715, A61K 31335, A61K 4700
Patent
active
054865085
ABSTRACT:
A pharmaceutical composition comprising a slightly water-soluble drug, a cyclodextrin and a water-soluble organic solvent is disclosed. The composition improves water-solubility and stability of the slightly water-soluble drug. The pharmaceutical composition is particularly suitable for injection preparations.
REFERENCES:
patent: 5024998 (1991-06-01), Bodor
M. Kurozumi, et al., "Inclusion compounds of non-steroidal antiflammatory and other slightly soluble drugs with alpha and beta cyclodextrins in powdered form.", Chemical and Pharmaceutical Bulletin, vol. 23, 1975, pp. 3062-3068.
Uekama, K., "Pharmaceutical Applications of Cyclodextrin Complexations," Yakugaku Zasshi 101 (10) 857-873 (1981).
Nishida Yoko
Ogawa Yasuaki
Uda Yoshiaki
Cintins Marianne M.
Conlin David G.
Lowen Cara Z.
Neuner George W.
Takeda Chemical Industries Ltd.
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