Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-08-09
1999-12-14
Travers, Russell
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 81, 514269, 514274, A01N 6700, A01N 4354, A01N 4390
Patent
active
060018410
ABSTRACT:
Oligonucleotide surrogates comprising a plurality of cyclobutyl moieties covalently joined by linking moieties are prepared and used as antisense diagnostics, therapeutics and research reagents. Methods of synthesis and use of both the oligonucleotide surrogates and intermediates thereof are disclosed.
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Baschang Gerhard
Cook Phillip Dan
ISIS Pharmaceuticals Inc.
Travers Russell
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