Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...
Patent
1981-04-08
1982-09-14
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Synthetic or structurally-modified peptidoglycan or...
549303, A61K 31365, C07D30793
Patent
active
043495656
ABSTRACT:
The invention relates to cyclobutanedicarboxisoimides of the formula I ##STR1## wherein one of X and Y is oxygen and the other is ##STR2## each of R.sub.1 and R.sub.6 independently is methyl or ethyl, each of R.sub.2 and R.sub.3 independently is hydrogen, fluorine or methyl, or R.sub.2 is aceto hydrogen or methyl, while R.sub.3 and R.sub.4 together can also form an additional valency in the 4-membered cycloaliphatic ring. These compounds are suitable for controlling a variety of phytopathogenic fungi. They can be obtained by cyclizing the corresponding cyclobutanedicarboxylic acid monoamides in the temperature range from about -20.degree. to +100.degree. C., in the presence of dehydrating agents such as acetic anhydride or N,N'-dicyclohexylcarbodiimide.
REFERENCES:
patent: 3990880 (1976-11-01), Mumford
patent: 4148625 (1979-04-01), Nagase
patent: 4179444 (1979-12-01), Roth
Derwent Abstract 26410W/16 (75).
Baumann Marcus
Bellus Daniel
Buhler Niklaus
Ciba-Geigy Corporation
Fan Jane T.
Rabin Frederick H.
Spitals John P.
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