Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2009-07-09
2010-06-22
Habte, Kahsay T (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S012000
Reexamination Certificate
active
07741320
ABSTRACT:
Compounds of formula (I):wherein:RCyrepresents an unsubstituted or substituted cycloalkyl group or cycloalkylalkyl group,R1, R2, R3and R4, which may be the same or different, each represent a hydrogen or halogen atom or a nitro group; a cyano group; a hydroxy group; an alkoxy group; an alkyl group; an unsubstituted or substituted amino group; a carboxy group; an alkoxycarbonyl group; an aryloxycarbonyl group; an unsubstituted or substituted aminocarbonyl group.Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator.
REFERENCES:
patent: 03/031422 (2003-04-01), None
Whitehead, Calvert, et al., “Diuretics. VI. 1,2,4-Benzothiadiazine 1,1-dioxides substituted at 2,3,4- and 7-N-Sulfamoyl positions” Journal of Organic Chemistry, vol. 27, p. 951-956, 1962.
Database caplus [online] Chemical Abstracts Service, “Hypertension. results of treatment [with various drugs]” Database accession No. 1964:12490.
Phillips, Dean, et al., “5′-alkyl-benzothiadiazides: a new subgroup of AMPA receptor modulators with improved affinity” Bioorganic & Medicinal Chemistry, vol. 10, No. 5, p. 1229-1248, 2002.
French Preliminary Search Report for FR0803898 of Feb. 19, 2009.
Caignard Daniel-Henri
Danober Laurence
De Tullio Pascal
Francotte Pierre
Lestage Pierre
Habte Kahsay T
Hueschen and Sage
Les Laboratoires Servier
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