Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2007-06-04
2008-11-18
Davis, Brian J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S452000, C564S455000, C564S457000, C514S674000
Reexamination Certificate
active
07453011
ABSTRACT:
Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
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Basu Hirak S.
Blokhin Andrei V.
Clifford, legal representative Linda
Marton Laurence J.
Reddy Venodhar K.
Davis Brian J
Morrison & Foerster / LLP
Progen Pharmaceuticals, Inc.
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