Cycloalkyl-substituted glutaramide diuretic agents

Details Cycloalkyl-substituted glutaramide diuretic agents Cycloalkyl-substituted glutaramide diuretic agents

1990-06-14

1991-07-30

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514530, 514563, 560 27, 560 44, 560116, 560118, 562450, 562498, 562500, A61K 3116, A61K 3119, A61K 31215, C07C27106

Patent

active

050361040

ABSTRACT:
2-Acylaminoalkyl-3-[1-(carboxycycloalkylcarbamoyl)cycloalkyl]propanoic acid derivatives (which may also be viewed as glutaramide derivatives) are useful in the treatment of hypertension, heart failure and renal insufficiency, based upon their inhibition of zinc-dependent, neutral endopiptidase.

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