Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-12-29
1995-09-19
Daus, Donald D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548217, 548219, 548156, 548169, 548235, 548478, 546176, 549 55, 549362, 549440, 549407, 544238, A61K 3142, C07D26356
Patent
active
054515963
ABSTRACT:
This invention relates to a class of novel polycyclic compounds containing a cycloalkyl ring having substituted thereon a primary amine and which is further linked or bridged to two mono- and/or bicyclic rings and which reduces levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.
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Dankulich William P.
Kiesow Terence J.
Learn Keith S.
Neuenschwander Kent W.
Scotese Anthony C.
Daus Donald D.
Nicholson James A.
Parker Raymond S.
Rhone Poulenc Rorer Pharmaceuticals Inc.
Savitzky Masrtin F.
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