Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1977-06-06
1979-02-06
Gerstl, Robert
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
562500, C07C17700
Patent
active
041385837
ABSTRACT:
Analogues of prostaglandins A, E, and F in which the C.sub.13 -C.sub.20 chain of the natural prostaglandins is replaced by a cycloalkenyl or a hydroxycycloalkenyl moiety such that vinylene radical and the hydroxyl group of the ring respectively retain their natural sequential positions at C.sub.13 -C.sub.14 and C.sub.15, inhibit aggregation of platelets in vitro and exhibit useful cardiovascular activity in vivo.
Arndt Henry C.
Biddlecom William G.
Peruzzotti George P.
Sih Charles J.
Woessner Warren D.
Gerstl Robert
Jeffers Jerome L.
Miles Laboratories Inc.
Sokolowski Myron B.
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