Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1977-12-23
1980-09-09
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424275, 424283, 2603452, 548253, 549 45, 549 46, 549 27, C07D25704, C07D31178, A61K 3135, A61K 3141
Patent
active
042218004
ABSTRACT:
Certain substituted cycloalkenochromones and pharmacologically acceptable salts thereof are disclosed as being useful in the treatment of allergies. The compounds have the structure: ##STR1## X is --O--, --S--, or --SO.sub.2. Y is from 1 to 4. R.sub.1 is H or alkyl, and R.sub.2 is H, alkyl, aryl, carboxyl, alkoxy, aralkoxy, or alkoxycarbonyl. When R.sub.1 is alkyl, R.sub.2 is hydrogen, alkyl or aryl. At least one of R.sub.2 and R.sub.3 is alkoxycarbonyl, carboxyl or tetrazolyl. R.sub.3 is carboxyl, alkylthio, alkylsulfonyl, alkylsulfinyl, alkoxycarbonyl, or tetrazolyl.
REFERENCES:
patent: 3232945 (1966-02-01), Sigal et al.
patent: 3244720 (1966-04-01), Meschino
patent: 3755319 (1973-08-01), Bays
patent: 3886162 (1975-05-01), Pfister et al.
patent: 3905989 (1975-09-01), Hodson et al.
patent: 3947449 (1976-03-01), Durchheimer et al.
Miller Thomas
Spicer John W.
Warren Brian T.
Hollrah Glennon H.
McNeil James D.
Miles Laboratories Inc.
Springer D. B.
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